Publications, Patents & Research
Research that advances knowledge
Peer-Reviewed Research
- 2020
Gene therapy delivering a paraoxonase 1 variant offers long-term prophylactic protection against nerve gases in mice
Betapudi, V., Goswami, R., Silayeva, L., Doctor, D., Chilukuri, N. — Science Translational Medicine
- 2016
Novel role for p56/Lck in the regulation of endothelial cell survival and angiogenesis
Betapudi, V., Shukla, M., Alluri, R., Merkulov, S., McCrae, K.R. — FASEB Journal
- 2012
Induction of endothelial cell microparticle release by antiphospholipid antibodies
Betapudi, V., McCrae, K.R. — Blood
- 2006
Distinct roles of non-muscle myosin II isoforms in cancer cell spreading and migration
Betapudi, V., Licate, L., Egelhoff, T.T. — Cancer Research
- 2005
A novel alpha kinase with a vWFA motif in Dictyostelium discoideum
Betapudi, V., Mason, C., Licate, L., Egelhoff, T.T. — Molecular Biology of the Cell
- 1994
Eggshell-bound starch phosphorylase packed bed reactor for continuous production of glucose-1-phosphate
Betapudi, V., Kumar, A. — Journal of Biotechnology
Scientific Reviews
Comprehensive review on gene therapy — senior author
Goswami et al. — Frontiers in Oncology, 2019
Patents
US Patent 5,965,393 · 1999
Method for enhancing foreign gene expression in baculovirus expression vector system
Sole inventor
Indian Patent 112/DEL/97 · 1997
Method for enhancing foreign gene expression in the baculovirus expression vector system
Sole inventor
US Provisional 62/475,502 · 2017
Recombinant AAV–Paraoxonase 1 F11 particles for prophylactic protection against G-type nerve agents
Sole inventor
Selected Research Contributions
Gene Therapy-Based Protection Against Neurotoxic Nerve Agents
Provides complete protection against neurotoxic nerve agents.
Betapudi et al., Science Translational Medicine, 2020
Discovery of Novel Protein Kinases
Elucidated the roles of these kinases in cell growth and development.
Molecular Biology of the Cell, 2005 and 2006
Nanoparticle-Based Therapeutic Development
Evaluated therapeutic efficacy of a nanoparticle approach to the disorder.
Journal of Thrombosis and Haemostasis, 2017
Anti-Tumor Angiogenic Activity of a Blood Coagulation Factor
Demonstrated its efficacy in suppressing angiogenesis and tumor growth.
FASEB Journal, 2016; Blood, 2016
Pathological Microvesicle Release in Antiphospholipid Syndrome
Identified mechanisms underlying pathological microvesicle release, including a cover-page research article.
Blood, 2012 and 2013
Double-Knockout Stable Cell Lines
A new method for generating double-knockout stable cell lines.
BioTechniques, 2004
Cancer Cell Migration and Metastasis
Revealed their contrasting roles in cancer cell migration and metastasis.
Cancer Research, 2006; Molecular Biology of the Cell, 2006
Wound Healing Mechanisms
Identified cytoskeletal activation as a key factor in cell migration and wound healing.
Experimental Cell Research, 2010
Glucose-1-Phosphate Bioreactor
Continuous production from starch solution.
Journal of Biotechnology, 1994
Widely Cited Gene Therapy Review
A widely cited review on gene therapy.
Goswami et al., Frontiers in Oncology, 2019